Miyazaki K, Mogi E, Araki N, Matsumoto G
Laboratory of Brain-operative expression, Brain Science Institute, RIKEN, Wako, Saitama, Japan.
Neuroreport. 1998 Dec 1;9(17):3943-8. doi: 10.1097/00001756-199812010-00032.
Single unit recording in rat nucleus accumbens (NAcc) was used to ascertain NAcc neuronal activity in mediating of reward including its anticipation. Of the 103 neurons investigated, 63% showed some response in connection with the task activity. Of these, 20 units responded during delivery of the primary reward (food and/or water) and five responded during the time period preceding reward if the reward was delayed (four to food, one to water). These result suggest that NAcc neurons responded not only to the delivery of primary reward and task inducing anticipation of reward, but also represent the difference of reward quality between food and water specifically.
在大鼠伏隔核(NAcc)中进行单单位记录,以确定伏隔核神经元在介导包括预期在内的奖赏过程中的活动。在研究的103个神经元中,63%在与任务活动相关时表现出某种反应。其中,20个单位在给予初级奖赏(食物和/或水)时做出反应,5个单位在奖赏延迟时在奖赏前的时间段内做出反应(4个对食物,1个对水)。这些结果表明,伏隔核神经元不仅对初级奖赏的给予和诱发奖赏预期的任务做出反应,而且还特别代表了食物和水之间奖赏质量的差异。