Franke C, Böhner H, Yang Q, Ohmann C, Röher H D
Department of General and Trauma Surgery, Heinrich-Heine-Universit at, Moorenstrasse 5, 40225 Düsseldorf, Germany.
World J Surg. 1999 Feb;23(2):141-6. doi: 10.1007/pl00013165.
A prospective multicenter observational trial was performed to assess the performance and clinical benefit of ultrasonography of the appendix in the routine clinical examination. Included in the study were 2280 patients with acute abdominal pain from 11 surgical departments in Germany and Austria. Ultrasonography of the appendix was performed in 870 (38%) of the patients (range 16-85%). The overall sensitivity of ultrasonography of the appendix was 55% (13-90%), the specificity 95% (range 82-100%), positive predictive value 81% (50-100%), and negative predictive value 85% (68-96%). With respect to single ultrasound scan findings, adequate sensitivity (44%) was achieved only with the target phenomen, not with the other criteria. There were no correlations between the ultrasound findings of the appendix and the diagnostic accuracy of the clinician, the negative appendectomy rate, or the perforated appendix rate. From the study it can be concluded that there is no proven clinical benefit of ultrasound scanning of the appendix in the routine clinical diagnosis.
进行了一项前瞻性多中心观察性试验，以评估阑尾超声检查在常规临床检查中的性能和临床益处。纳入研究的有来自德国和奥地利11个外科科室的2280例急性腹痛患者。其中870例（38%）（范围为16 - 85%）患者接受了阑尾超声检查。阑尾超声检查的总体敏感性为55%（13 - 90%），特异性为95%（范围为82 - 100%），阳性预测值为81%（50 - 100%），阴性预测值为85%（68 - 96%）。就单次超声扫描结果而言，仅通过目标现象可获得足够的敏感性（44%），其他标准则无法达到。阑尾的超声检查结果与临床医生的诊断准确性、阴性阑尾切除率或阑尾穿孔率之间无相关性。从该研究可以得出结论，在常规临床诊断中，阑尾超声扫描未显示出已证实的临床益处。
