Weiss E, Buchholz I, Schweigert F J
Abteilung Traumatologie, Chirurgischen Klinik am Parkkrankenhaus Leipzig-Dösen.
Zentralbl Chir. 1998;123(11):1277-83.
In 17 patients with osteitis and 16 polytraumatized patients changes in the plasma levels of vitamin A, vitamin E and beta-carotene were investigated. Plasma samples taken preoperatively, daily during the first three days and then twice a week postoperatively were analysed for fat-soluble vitamins by high performance liquid chromatography (HPLC). Significant changes in plasma levels of all three components depending on the outcome of injury were found in all patients. Increased levels were observed in patients that survived the injury, while in those who died a significant decrease was observed. Recommendations regarding the supplementation with these vitamins in clinical practice can not be made based on these results, but substitute might prove beneficial for vitamin E in certain types of injury.
对17例骨炎患者和16例多发伤患者的血浆维生素A、维生素E和β-胡萝卜素水平变化进行了研究。术前、术后头三天每天以及术后每周两次采集的血浆样本，通过高效液相色谱法（HPLC）分析脂溶性维生素。在所有患者中均发现，这三种成分的血浆水平根据损伤结果有显著变化。受伤后存活的患者中观察到水平升高，而死亡患者中则观察到显著下降。基于这些结果无法给出临床实践中补充这些维生素的建议，但在某些类型的损伤中，补充剂可能对维生素E有益。
