Gupta M A, Gupta A K
Department of Psychiatry, University of Western Ontario, London, Ontario,
Br J Dermatol. 1998 Nov;139(5):846-50. doi: 10.1046/j.1365-2133.1998.02511.x.
We examined the prevalence of depression (measured by the Carroll Rating Scale for Depression, CRSD), wishes to be dead and acute suicidal ideation among 480 patients with dermatological disorders that may be cosmetically disfiguring, i.e. non-cystic facial acne (n = 72; 5.6% suicidal ideation), alopecia areata (n = 45; 0% suicidal ideation), atopic dermatitis (n = 146; 2.1% suicidal ideation) and psoriasis (79 outpatients, 2.5% suicidal ideation and 138 inpatients, 7.2% suicidal ideation). Analysis of variance revealed that the severely affected psoriasis inpatients (mean +/- SD total body surface area affected: 52 +/- 23.4%) had the highest (P < 0.05) CRSD score, followed by the patients with mild to moderate acne; both scores were in the range for clinical depression (CRSD score > 10). The 5.6-7.2% prevalence of active suicidal ideation among the psoriasis and acne patients was higher than the 2.4-3.3% prevalence reported among general medical patients. Our findings highlight the importance of recognizing psychiatric comorbidity, especially depression, among dermatology patients and indicate that in some instances even clinically mild to moderate disease such as non-cystic facial acne can be associated with significant depression and suicidal ideation.
我们对480例可能存在美容缺陷的皮肤病患者进行了抑郁症患病率(采用卡罗尔抑郁评定量表,CRSD测量)、想死愿望及急性自杀意念的调查,这些皮肤病包括非囊性面部痤疮(n = 72;自杀意念发生率5.6%)、斑秃(n = 45;自杀意念发生率0%)、特应性皮炎(n = 146;自杀意念发生率2.1%)和银屑病(79例门诊患者,自杀意念发生率2.5%;138例住院患者,自杀意念发生率7.2%)。方差分析显示,重度银屑病住院患者(平均±标准差受累体表面积:52±23.4%)的CRSD评分最高(P < 0.05),其次是轻至中度痤疮患者;两者评分均处于临床抑郁症范围内(CRSD评分>10)。银屑病和痤疮患者中5.6 - 7.2%的活跃自杀意念发生率高于普通内科患者报告的2.4 - 3.3%的发生率。我们的研究结果强调了认识皮肤病患者精神共病尤其是抑郁症的重要性,并表明在某些情况下,即使是临床轻至中度疾病如非囊性面部痤疮也可能与显著的抑郁症和自杀意念相关。