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[实验性动脉粥样硬化发展过程中主动脉平滑肌细胞的收缩特性]

[Contractile properties of the smooth muscle cells of the aorta during development of experimental atherosclerosis].

作者信息

Kodner A S

出版信息

Biull Eksp Biol Med. 1976 Sep;82(9):1036-8.

PMID:990451
Abstract

Experiments were conducted on the isolated ring-shaped segments of rabbit aorta; the contractile reactions of the smooth muscle cells under the effect of catecholamines and KC1 were investigated at 27 and 37 degrees C both under normal conditions and at the initial stages of atherosclerosis. The contractile reactions of the atherosclerotic aorta stimulated by KC1 were lower in amplitude than those of the intact one; the opposite shifts were observed under the action of catecholamines. A decrease of the temperature reduced the contractile responses both under normal conditions and in atherosclerosis.

摘要

在兔主动脉离体环形节段上进行实验;研究了在27℃和37℃下,正常条件以及动脉粥样硬化初始阶段,平滑肌细胞在儿茶酚胺和氯化钾作用下的收缩反应。氯化钾刺激下,动脉粥样硬化主动脉的收缩反应幅度低于正常主动脉;而在儿茶酚胺作用下则观察到相反的变化。温度降低会使正常条件下以及动脉粥样硬化状态下的收缩反应均减弱。

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