Skvaril F, Barandun S, Kuffer F, Probst M
Blut. 1976 Oct;33(4):281-4. doi: 10.1007/BF00995225.
In sera of normal individuals of different age groups the kappa- and lambda-type immunoglobulins were measured and the kappa/lambda ratio was calculated. The relative concentration of lambda-immunoglobulins in sera of newborns and young children was found to be significantly higher than in the adult sera. The well-known asynchronous maturation of immunoglobulin classes and IgG subclasses in the early childhood is evidently accompagnied by a asynchronous maturation of immunoglobulin types.
在不同年龄组正常个体的血清中，检测了κ型和λ型免疫球蛋白，并计算了κ/λ比值。发现新生儿和幼儿血清中λ免疫球蛋白的相对浓度明显高于成人血清。幼儿期众所周知的免疫球蛋白类别和IgG亚类的不同步成熟显然伴随着免疫球蛋白类型的不同步成熟。
