Genuth S M, Houser H B, Carter J R, Merkatz I, Price J W, Schumacher O P, Wieland R G
Diabetes. 1976 Dec;25(12):1110-7. doi: 10.2337/diab.25.12.1110.
The Diabetes Association of greater Cleveland screened 307,000 individuals in the metropolitan area for diabetes with a 75-gm. oral load of carbohydrate. Of these subjects 12,600 (4.1 per cent) had a two-capillary blood glucose level of greater than 139 mg. per cent and were defined as positive. Seventy per cent of the positives were retested, and 65 per cent of these again had two-hour levels greater than 139 mg. per cent. Seventy-one per cent of the original screening values were between 104 and 199 mg. per cent. The rate of positivity on retesting increased with the original screening bracket reaching 90 per cent at an original screening level of 240 mg. per cent or higher. The frequency of positive retests also increased with age irrespective of whether the original screening level was less than or greater than 200 mg. per cent. The implications of this large detection experience for conducting future mass surveys for diabetes are discussed.
大克利夫兰糖尿病协会对该大都市地区的30.7万人进行了糖尿病筛查,采用75克碳水化合物的口服负荷试验。在这些受试者中,12600人(4.1%)的双毛细血管血糖水平高于139毫克/百分比,被定义为阳性。70%的阳性者进行了重新检测,其中65%的人两小时血糖水平再次高于139毫克/百分比。71%的原始筛查值在104至199毫克/百分比之间。重新检测时的阳性率随着原始筛查范围的增加而增加,在原始筛查水平为240毫克/百分比或更高时达到90%。无论原始筛查水平是低于还是高于200毫克/百分比,重新检测呈阳性的频率也随着年龄的增长而增加。本文讨论了这一大型检测经验对未来开展糖尿病大规模调查的意义。