Harrison S L, Buettner P G, MacLennan R
School of Public Health and Tropical Medicine, James Cook University, Townsville, Queensland, Australia.
Arch Dermatol. 1999 Jan;135(1):47-52. doi: 10.1001/archderm.135.1.47.
To investigate the body-site distribution of melanocytic nevi (MN) with respect to habitually and intermittently sun-exposed surfaces.
Cross-sectional survey of MN prevalence.
Townsville (19.16 degrees S), Queensland, Australia.
Random sample of 506 1- to 6-year-old white children who were born and raised in Townsville (response, 87.6%).
Site-specific counts and densities (number per square meter) of MN.
Densities of MN of all sizes were highest on the outer forearms, followed by the outer upper arms, neck, and face. The feet had the lowest density of MN. Densities of MN of 2 mm or greater were highest on the upper arms and trunk. Boys had higher densities of MN of all sizes on the neck than girls (P = .002). Girls had higher densities of MN of 2 mm or greater on the lower legs (P = .006) and thighs (P = .005) than boys. Habitually sun-exposed body sites had higher densities, particularly of small MN, than relatively sun-protected sites, and larger MN were most prevalent on the intermittently exposed skin of the trunk.
These children have higher total body and site-specific MN counts and densities than children from elsewhere, and their MN are distributed over the body in a way that implicates exposure to sunlight. As sun exposure in childhood and MN are risk factors for melanoma, intervention studies are required to determine if MN can be prevented.
研究黑素细胞痣（MN）在经常和偶尔暴露于阳光下的体表部位的分布情况。
MN患病率的横断面调查。
澳大利亚昆士兰州汤斯维尔（南纬19.16度）。
对506名在汤斯维尔出生并长大的1至6岁白人儿童进行随机抽样（应答率为87.6%）。
MN的部位特异性计数和密度（每平方米数量）。
各种大小MN的密度在前臂外侧最高，其次是上臂外侧、颈部和面部。足部MN的密度最低。2毫米或更大的MN密度在上臂和躯干最高。男孩颈部各种大小MN的密度高于女孩（P = 0.002）。女孩小腿（P = 0.006）和大腿（P = 0.005）上2毫米或更大MN的密度高于男孩。经常暴露于阳光下的身体部位，特别是小MN的密度，高于相对防晒的部位，较大的MN在躯干偶尔暴露的皮肤上最为普遍。
这些儿童的全身和部位特异性MN计数及密度高于其他地区的儿童，且其MN在身体上的分布方式表明与阳光照射有关。由于儿童期阳光照射和MN是黑色素瘤的危险因素，需要进行干预研究以确定MN是否可以预防。
