三种单细胞真核生物中DNA甲基化的比较研究。
Comparative study of DNA methylation in three unicellular eucaryotes.
作者信息
Hattman S, Kenny C, Berger L, Pratt K
出版信息
J Bacteriol. 1978 Sep;135(3):1156-7. doi: 10.1128/jb.135.3.1156-1157.1978.
Abstract
We have analyzed the nature/content of methylated bases in the nuclear DNA of three unicellular eucaryotes. The pattern of methylation was different for each of the three organisms studied: Saccharomyces cerevisiae contained only 5-methylcytosine; Tetrahymena pyriformis contained only N6-methyladenine; and Chlamydomonas reinhardi contained both modified bases.
摘要
我们分析了三种单细胞真核生物核DNA中甲基化碱基的性质/含量。在所研究的三种生物中，每种生物的甲基化模式都不同：酿酒酵母仅含有5-甲基胞嘧啶；梨形四膜虫仅含有N6-甲基腺嘌呤；莱茵衣藻则同时含有这两种修饰碱基。
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