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暴露于高温后胎儿仓鼠出现无脑畸形。

Exencephaly in fetal hamsters following exposure to hyperthermia.

作者信息

Kilham L, Ferm V H

出版信息

Teratology. 1976 Dec;14(3):323-6. doi: 10.1002/tera.1420140307.

DOI:10.1002/tera.1420140307
PMID:996779
Abstract

Exposure of pregnant hamsters on gestation day 8 to 40 or 41 degrees C for one hour caused an increased rate of resorption and a high frequency of exencephaly and encephalocele. Longer exposures often killed pregnant females. Hamsters that had fetuses with abnormalities usually experienced body temperature elevations of 3-4 degrees C above normal (37 degrees C).

摘要

怀孕的仓鼠在妊娠第8天暴露于40或41摄氏度环境1小时,会导致吸收率增加以及无脑儿和脑膨出的高发生率。暴露时间更长通常会导致怀孕母鼠死亡。怀有异常胎儿的仓鼠体温通常比正常体温(37摄氏度)高出3至4摄氏度。

相似文献

1
Exencephaly in fetal hamsters following exposure to hyperthermia.暴露于高温后胎儿仓鼠出现无脑畸形。
Teratology. 1976 Dec;14(3):323-6. doi: 10.1002/tera.1420140307.
2
Hyperthermia-induced exencephaly in mice: effect of multiple exposures.热诱导小鼠无脑畸形:多次暴露的影响。
Teratology. 1988 Jan;37(1):37-42. doi: 10.1002/tera.1420370107.
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Environmental heat stress effects in the hamster.
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Synergistic teratogenic effects of arsenic and hyperthermia in hamsters.砷与高温对仓鼠的协同致畸作用。
Environ Res. 1977 Dec;14(3):483-6. doi: 10.1016/0013-9351(77)90055-x.
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Effects of high environmental temperatures on the development of rabbit embryos.高温环境对兔胚胎发育的影响。
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The induction of microphthalmia, encephalocele, and other head defects following hyperthermia during the gastrulation process in the rat.
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Teratogenic interaction of hyperthermia and vitamin A.
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Thermoregulation in pregnancy. Implications for exercise.孕期体温调节。对运动的影响。
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Arsenic as a teratogenic agent.砷作为一种致畸剂。
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Association of foetal wastage with influenza infection during ferret pregnancy.雪貂孕期流感感染与胎儿流失的关联。
Br J Exp Pathol. 1978 Apr;59(2):190-5.
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Non-Mendelian development defects: animal models and implications for research into human disease.非孟德尔式发育缺陷:动物模型及其对人类疾病研究的意义
Bull World Health Organ. 1977;55(4):475-87.
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[Developmental abnormalities of non-mendelian origin: animal models and possible applications to research on human diseases].[非孟德尔遗传起源的发育异常:动物模型及其在人类疾病研究中的潜在应用]
Bull World Health Organ. 1978;56(1):83-97.