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两种海洋物种中2,4-二氯苯氧乙酸和苯乙酸的牛磺酸结合作用

Taurine conjugation of 2,4-dichlorophenoxyacetic acid and phenylacetic acid in two marine species.

作者信息

James M O, Bend J R

出版信息

Xenobiotica. 1976 Jul;6(7):393-8. doi: 10.3109/00498257609151651.

Abstract
  1. At least 50% of a dose of 14C-labelled 2,4-dichlorophenoxyacetic acid or phenylacetic acid was excreted in urine in 48 hours after administration to dogfish shark or flounder. 2. For both compounds, more than 90% of the urinary 14C was present as a single metabolite. 3. Each metabolite was the taurine conjugate of the administered compound.
摘要
  1. 给角鲨或比目鱼注射14C标记的2,4-二氯苯氧乙酸或苯乙酸后,在48小时内至少50%的剂量经尿液排出。2. 对于这两种化合物,超过90%的尿中14C以单一代谢物的形式存在。3. 每种代谢物都是所给药化合物的牛磺酸共轭物。

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