乙醇对恒河猴长期服用左旋 - α - 乙酰美沙醇（LAAM）代谢的影响。
The effect of ethanol on the metabolism of chronically-administered l-alpha-acetylmethadol (LAAM) in the rhesus monkey.
作者信息
Casella G A, Deneau G A, Mule S J
出版信息
Res Commun Chem Pathol Pharmacol. 1978 Aug;21(2):351-4.
PMID:99782
Abstract
The metabolism of 3H-LAAM was studied in monkeys treated acutely and chronically with 2 mg/kg LAAM via intragastric catheter three times weekly. From the 15th week, 250 mg/kg ethanol every 2 hours (3g/kg/day) was also administered. This dose of ethanol did not impair the metabolism of LAAM in monkeys.
摘要
通过胃内导管每周三次给猴子急性和慢性注射2毫克/千克的左旋-α-乙酰美沙酮（LAAM），研究了3H-LAAM的代谢情况。从第15周开始，每2小时还给予250毫克/千克乙醇（3克/千克/天）。该剂量的乙醇并未损害猴子体内LAAM的代谢。
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The effect of ethanol on the metabolism of chronically-administered l-alpha-acetylmethadol (LAAM) in the rhesus monkey.乙醇对恒河猴长期服用左旋 - α - 乙酰美沙醇（LAAM）代谢的影响。
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