Olsovsky M R, Shorofsky S R, Gold M R
Department of Medicine, University of Maryland, Baltimore.
Pacing Clin Electrophysiol. 1999 Jan;22(1 Pt 2):165-8. doi: 10.1111/j.1540-8159.1999.tb00325.x.
Shock impedance is an important determinant of defibrillation efficacy. Lead configuration, shock polarity, and delivered energy can affect shock impedance, but these variables have not been studied in active can lead systems. The present study was a prospective evaluation of 25 patients undergoing initial transvenous defibrillator implantation. In all patients, a dual coil lead and pectoral emulator were placed and three lead configurations were tested in random order: Lead (distal to proximal coil), unipolar (distal coil to can), and triad (distal coil to can + proximal coil). Shock energies of 0.1- to 15-J shock were evaluated. Impedance increased a mean of 21% as delivered energy was decreased (P < 0.001), an effect independent of lead configuration. At all delivered energies, impedances in the unipolar configuration were about 40% higher than triad, while the lead configuration was about 20% higher than triad (ps < 0.001). Polarity did not affect impedance. These results indicate that transvenous lead configurations and delivered energy, but not polarity, significantly influence shock impedance. The magnitude of the increase of impedance at low energies is independent of the shocking pathway. This effect has important implications for low energy shocks used to terminate atrial fibrillation or ventricular tachycardia.
除颤阻抗是除颤效果的一个重要决定因素。导联配置、电击极性和输送能量会影响除颤阻抗,但这些变量在主动式罐体导联系统中尚未得到研究。本研究是对25例首次接受经静脉植入除颤器的患者进行的前瞻性评估。在所有患者中,均植入了双线圈导联和胸肌模拟器,并以随机顺序测试了三种导联配置:导联(从远端线圈到近端线圈)、单极(从远端线圈到罐体)和三联(从远端线圈到罐体 + 近端线圈)。评估了0.1至15焦耳的电击能量。随着输送能量的降低,阻抗平均增加21%(P < 0.001),这一效应与导联配置无关。在所有输送能量下,单极配置的阻抗比三联配置高约40%,而导联配置比三联配置高约20%(P < 0.001)。极性不影响阻抗。这些结果表明,经静脉导联配置和输送能量,而非极性,会显著影响除颤阻抗。低能量时阻抗增加的幅度与电击路径无关。这一效应对于用于终止心房颤动或室性心动过速的低能量电击具有重要意义。