Gustafsson B, Carstensen J
Department of Paediatrics, Huddinge Hospital, Karolinska Institute, Sweden.
Br J Cancer. 1999 Feb;79(3-4):655-7. doi: 10.1038/sj.bjc.6690103.
We have examined 645 recorded cases of childhood acute lymphatic leukaemia (ALL) in Sweden during 1973-89 to identify space-time clustering by using the close-pair method of Knox. The records included date of birth and of diagnosis as well as addresses at birth and at diagnosis. There was a significant excess of case pairs close in date of birth and place of birth in the 5- to 15-year age group.
我们调查了1973年至1989年期间瑞典记录的645例儿童急性淋巴细胞白血病(ALL)病例,采用诺克斯近距离配对法来确定时空聚集性。记录包括出生日期、诊断日期以及出生时和诊断时的地址。在5至15岁年龄组中,出生日期和出生地相近的病例对显著过多。