Belfroid A C, Van der Horst A, Vethaak A D, Schäfer A J, Rijs G B, Wegener J, Cofino W P
Institute for Environmental Studies, Free University, Amsterdam, The Netherlands.
Sci Total Environ. 1999 Jan 12;225(1-2):101-8. doi: 10.1016/s0048-9697(98)00336-2.
An analytical procedure was developed that enables routine analysis of four estrogenic hormones in concentrations below 1 ng/l in surface water and waste water. The recovery was 88-98% with a limit of detection of 0.1-2.4 ng/l depending on the compound and the matrix measured. This method was used to determine the occurrence of 17 beta-estradiol, 17 alpha-estradiol, estrone and 17 alpha-ethinylestradiol in the aquatic environment in The Netherlands. The data show that estrogenic hormones can be detected at low concentrations (up to 6 ng/l) at some locations in surface water. In selected effluents of waste water treatment plants estrone and 17 beta-estradiol were detected in concentrations in the ng/l range. Concentrations of 17 alpha-estradiol and the contraceptive 17 alpha-ethinylestradiol were in most of these samples below the limit of detection. Hormone glucuronides were not detected in most surface water and effluents.
开发了一种分析方法，可对地表水和废水中浓度低于1 ng/l的四种雌激素进行常规分析。回收率为88-98%，检测限为0.1-2.4 ng/l，具体取决于所测化合物和基质。该方法用于测定荷兰水生环境中17β-雌二醇、17α-雌二醇、雌酮和17α-乙炔雌二醇的存在情况。数据表明，在地表水的某些位置可以检测到低浓度（高达6 ng/l）的雌激素。在选定的污水处理厂排放物中，检测到雌酮和17β-雌二醇的浓度在ng/l范围内。在大多数这些样品中，17α-雌二醇和避孕药17α-乙炔雌二醇的浓度低于检测限。在大多数地表水和排放物中未检测到激素葡萄糖醛酸苷。
