Mitchell A P
Department of Microbiology, Institute of Cancer Research, Columbia University, 701 West 168th Street, New York, NY 10032, USA.
Curr Opin Microbiol. 1998 Dec;1(6):687-92. doi: 10.1016/s1369-5274(98)80116-1.
Two regulatory pathways govern filamentation in the pathogenic fungus Candida albicans. Recent virulence studies of filamentation regulatory mutants argue that both yeast and filamentous forms have roles in infection. Filamentation control pathways seem closely related in C. albicans and in Saccharomyces cerevisiae, thus permitting speculation about C. albicans filamentation genes not yet discovered.
两条调控途径控制着致病性真菌白色念珠菌的菌丝形成。最近对菌丝形成调控突变体的毒力研究表明，酵母形式和丝状形式在感染过程中都发挥作用。白色念珠菌和酿酒酵母中的菌丝形成控制途径似乎密切相关，因此可以推测尚未发现的白色念珠菌菌丝形成基因。
