Kim S Y, Gao J J, Lee W C, Ryu K S, Lee K R, Kim Y C
Dept. of Sericulture & Entomology, National Institute Agricultural Science and Technology, RDA, Suwon, Korea.
Arch Pharm Res. 1999 Feb;22(1):81-5. doi: 10.1007/BF02976442.
Nine flavonoids (1-9) were isolated from the leaves of Morus alba (Moraceae). The structures of compounds were determined to be kaempferol-3-O-beta-D-glucopyranoside (astragalin, 1) kaempferol-3-O-(6"-O-acetyl)-beta-D-glucopyranoside (2), quercetin-3-O-(6"-O-acetyl)-beta-D-glucopyranoside (3), quercetin-3-O-beta-D-glucopyranoside (4), kaempferol-3-O-alpha-L-rhamnopyranosyl-(1-->6)-beta-D-glucopyranoside (5), quercetin-3-O-alpha-L-rhamnopyranosyl-(1-->6)-beta-D-glucopyranoside (rutin, 6), quercetin-3-O-beta-D-glucopyranosyl-(1-->6)-beta-D-glucopyranoside (7), quercetin-3,7-di-O-beta-D-glucopyranoside (8) and quercetin (9) on the basis of spectroscopic and chemical studies. Compounds 7 and 9 exhibited significant radical scavenging effect on 1,1-diphenyl-2-picrylhydrazyl radical.
从桑科植物桑（Morus alba）的叶子中分离出了九种黄酮类化合物（1-9）。通过光谱和化学研究确定，化合物的结构分别为山奈酚-3-O-β-D-吡喃葡萄糖苷（紫云英苷，1）、山奈酚-3-O-（6″-O-乙酰基）-β-D-吡喃葡萄糖苷（2）、槲皮素-3-O-（6″-O-乙酰基）-β-D-吡喃葡萄糖苷（3）、槲皮素-3-O-β-D-吡喃葡萄糖苷（4）、山奈酚-3-O-α-L-鼠李吡喃糖基-（1→6）-β-D-吡喃葡萄糖苷（5）、槲皮素-3-O-α-L-鼠李吡喃糖基-（1→6）-β-D-吡喃葡萄糖苷（芦丁，6）、槲皮素-3-O-β-D-吡喃葡萄糖基-（1→6）-β-D-吡喃葡萄糖苷（7）、槲皮素-3,7-二-O-β-D-吡喃葡萄糖苷（8）和槲皮素（9）。化合物7和9对1,1-二苯基-2-苦基肼自由基表现出显著的自由基清除作用。
