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针对高危汽车工人的营养干预:下一步试验结果

Nutrition intervention for high-risk auto workers: results of the Next Step Trial.

作者信息

Tilley B C, Glanz K, Kristal A R, Hirst K, Li S, Vernon S W, Myers R

机构信息

Department of Biostatistics and Research Epidemiology, Henry Ford Health Sciences Center, Detroit, Michigan, USA.

出版信息

Prev Med. 1999 Mar;28(3):284-92. doi: 10.1006/pmed.1998.0439.

Abstract

BACKGROUND

The Next Step Trial tested interventions encouraging prevention and early detection practices in automotive-industry employees at increased colorectal cancer risk. This article describes results of the nutrition intervention promoting low-fat, high-fiber eating patterns.

METHODS

Twenty-eight worksites (5,042 employees at baseline) were randomized to a 2-year nutrition intervention including classes, mailed self-help materials, and personalized dietary feedback. Control worksites received no intervention. Nutrition outcomes were assessed by mailed food frequency questionnaires (FFQs) Primary nutrition outcomes included percentage energy from fat and fiber density (g/1,000 kcal) at 1 year postrandomization. Secondary outcomes included servings of fruits/vegetables and dietary measures at 2 years postrandomization. Analyses were adjusted for within worksite correlations and baseline covariates. Fifty-eight percent of employees returned FFQs.

RESULTS

At 1 year, there were modest but statistically significant intervention effects for fat (-0.9 %en), fiber (+0.5 g/1,000 kcal), and fruits/vegetables (+0.2 servings/day) (all P < 0.007). At 2 years, due to significant positive changes in control worksites, intervention effects were smaller, significant for fiber only. Intervention effects were larger in younger (<50 years), active employees and class attendees.

CONCLUSION

The nutrition intervention produced significant but modest effects on dietary fat and fiber and fruits/vegetables in these high-risk employees. Age and dose effects suggest younger employees may be more responsive to this intervention.

摘要

背景

“下一步试验”测试了旨在鼓励汽车行业中患结直肠癌风险增加的员工进行预防和早期检测的干预措施。本文描述了促进低脂、高纤维饮食模式的营养干预结果。

方法

28个工作场所(基线时5042名员工)被随机分为接受为期2年的营养干预组,干预包括课程、邮寄自助材料和个性化饮食反馈。对照工作场所未接受干预。通过邮寄食物频率问卷(FFQ)评估营养结果。主要营养结果包括随机分组后1年时脂肪供能百分比和纤维密度(克/1000千卡)。次要结果包括随机分组后2年时水果/蔬菜的摄入量和饮食指标。分析对工作场所内的相关性和基线协变量进行了调整。58%的员工返回了FFQ。

结果

1年时,脂肪(-0.9%能量)、纤维(+0.5克/1000千卡)和水果/蔬菜(+0.2份/天)有适度但具有统计学意义的干预效果(所有P<0.007)。2年时,由于对照工作场所出现显著的积极变化,干预效果较小,仅纤维有显著效果。年轻(<50岁)、活跃的员工和参加课程的员工干预效果更大。

结论

营养干预对这些高危员工的饮食脂肪、纤维和水果/蔬菜产生了显著但适度的影响。年龄和剂量效应表明年轻员工可能对这种干预反应更敏感。

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