Aoki N, Kitamura T, Tominaga T, Fukumori N, Sakamoto Y, Kato K, Mori M
Division of Pathology, Department of Toxicology, Tokyo Metropolitan Research Laboratory of Public Health, Hyakunincho, Shinjukuku, Tokyo 169, Japan.
J Clin Microbiol. 1999 Apr;37(4):1165-7. doi: 10.1128/JCM.37.4.1165-1167.1999.
We performed immunohistochemical staining on the nontumorous renal tissue of 45 patients with renal cancer but without progressive multifocal encephalopathy using JCV-specific antibody. For one patient we found positive staining of the nuclei of the renal collecting ducts. Immunoelectron microscopic examination of the positive cell nuclei revealed electron-dense polyomavirus-like particles.
我们使用JC病毒特异性抗体，对45例患有肾癌但无进行性多灶性白质脑病的患者的非肿瘤性肾组织进行了免疫组织化学染色。对于一名患者，我们发现肾集合管细胞核呈阳性染色。对阳性细胞核进行免疫电子显微镜检查，发现了电子致密的多瘤病毒样颗粒。
