在一名患有肾癌但无进行性多灶性白质脑病患者的非肿瘤性肾组织中对JC病毒进行免疫组织化学检测。
Immunohistochemical detection of JC virus in nontumorous renal tissue of a patient with renal cancer but without progressive multifocal leukoencephalopathy.
作者信息
Aoki N, Kitamura T, Tominaga T, Fukumori N, Sakamoto Y, Kato K, Mori M
机构信息
Division of Pathology, Department of Toxicology, Tokyo Metropolitan Research Laboratory of Public Health, Hyakunincho, Shinjukuku, Tokyo 169, Japan.
出版信息
J Clin Microbiol. 1999 Apr;37(4):1165-7. doi: 10.1128/JCM.37.4.1165-1167.1999.
Abstract
We performed immunohistochemical staining on the nontumorous renal tissue of 45 patients with renal cancer but without progressive multifocal encephalopathy using JCV-specific antibody. For one patient we found positive staining of the nuclei of the renal collecting ducts. Immunoelectron microscopic examination of the positive cell nuclei revealed electron-dense polyomavirus-like particles.
摘要
我们使用JC病毒特异性抗体，对45例患有肾癌但无进行性多灶性白质脑病的患者的非肿瘤性肾组织进行了免疫组织化学染色。对于一名患者，我们发现肾集合管细胞核呈阳性染色。对阳性细胞核进行免疫电子显微镜检查，发现了电子致密的多瘤病毒样颗粒。
相似文献
1
Immunohistochemical detection of JC virus in nontumorous renal tissue of a patient with renal cancer but without progressive multifocal leukoencephalopathy.在一名患有肾癌但无进行性多灶性白质脑病患者的非肿瘤性肾组织中对JC病毒进行免疫组织化学检测。
J Clin Microbiol. 1999 Apr;37(4):1165-7. doi: 10.1128/JCM.37.4.1165-1167.1999.
2
A Difficult Decision: Atypical JC Polyomavirus Encephalopathy in a Kidney Transplant Recipient.艰难抉择：肾移植受者中的非典型JC多瘤病毒脑病
Transplantation. 2017 Jun;101(6):1461-1467. doi: 10.1097/TP.0000000000001275.
3
Immunosuppression increases JC polyomavirus large T antigen DNA load in the brains of patients without progressive multifocal leukoencephalopathy.免疫抑制会增加无进行性多灶性白质脑病患者大脑中的 JC 多瘤病毒大 T 抗原 DNA 载量。
J Infect Dis. 2013 Jan 1;207(1):133-6. doi: 10.1093/infdis/jis668. Epub 2012 Oct 30.
4
New JC virus infection patterns by in situ polymerase chain reaction in brains of acquired immunodeficiency syndrome patients with progressive multifocal leukoencephalopathy.采用原位聚合酶链反应检测获得性免疫缺陷综合征合并进行性多灶性白质脑病患者脑内新型JC病毒感染模式
J Neurovirol. 2004 Feb;10(1):1-11. doi: 10.1080/13550280490269691.
5
Immunosuppression increases latent infection of brain by JC polyomavirus.免疫抑制会增加 JC 多瘤病毒对大脑的潜伏感染。
Pathology. 2011 Jun;43(4):362-7. doi: 10.1097/PAT.0b013e3283463558.
6
Polyoma nephropathy and progressive multifocal leukoencephalopathy in a renal transplant recipient.一名肾移植受者发生的多瘤病毒肾病和进行性多灶性白质脑病。
J Child Neurol. 2004 Apr;19(4):301-4. doi: 10.1177/088307380401900412.
7
Progressive multifocal leukoencephalopathy: simultaneous detection of JCV DNA and anti-JCV antibodies in the cerebrospinal fluid.进行性多灶性白质脑病：脑脊液中JC病毒DNA和抗JC病毒抗体的同时检测
Eur J Neurol. 2000 Jan;7(1):101-6. doi: 10.1046/j.1468-1331.2000.00009.x.
8
The clinical utility of JC virus antibody index measurements in the context of progressive multifocal leukoencephalopathy.JC 病毒抗体指数测量在进行性多灶性白质脑病中的临床效用。
Acta Neurol Scand. 2017 Nov;136 Suppl 201:37-44. doi: 10.1111/ane.12840.
9
Traffic of JC virus from sites of initial infection to the brain: the path to progressive multifocal leukoencephalopathy.JC病毒从初始感染部位至脑部的传播：通往进行性多灶性白质脑病之路。
J Infect Dis. 2002 Dec 1;186 Suppl 2:S180-6. doi: 10.1086/344280.
10
Association of JC virus with tubulointerstitial nephritis in a renal allograft recipient.肾移植受者中JC病毒与肾小管间质性肾炎的关联。
J Med Virol. 2004 Apr;72(4):675-8. doi: 10.1002/jmv.20037.
引用本文的文献
1
Human polyomavirus receptor distribution in brain parenchyma contrasts with receptor distribution in kidney and choroid plexus.人多瘤病毒受体在脑实质中的分布与在肾脏和脉络丛中的受体分布形成对比。
Am J Pathol. 2015 Aug;185(8):2246-58. doi: 10.1016/j.ajpath.2015.04.003. Epub 2015 Jun 6.
2
The role of polyomaviruses in human disease.多瘤病毒在人类疾病中的作用。
Virology. 2009 Feb 20;384(2):266-73. doi: 10.1016/j.virol.2008.09.027. Epub 2008 Nov 7.
3
Detection of the archetypal regulatory region of JC virus from the tonsil tissue of patients with tonsillitis and tonsilar hypertrophy.从扁桃体炎和扁桃体肥大患者的扁桃体组织中检测JC病毒的原型调控区。
J Neurovirol. 2004 Aug;10(4):244-9. doi: 10.1080/13550280490468663.
4
Differential distribution of the JC virus receptor-type sialic acid in normal human tissues.人正常组织中JC病毒受体型唾液酸的差异分布。
Am J Pathol. 2004 Feb;164(2):419-28. doi: 10.1016/S0002-9440(10)63132-X.
本文引用的文献
1
Persistent JC virus (JCV) infection is demonstrated by continuous shedding of the same JCV strains.持续的JC病毒（JCV）感染通过相同JCV毒株的持续排出得以证实。
J Clin Microbiol. 1997 May;35(5):1255-7. doi: 10.1128/jcm.35.5.1255-1257.1997.
2
Antibody against synthetic multiple antigen peptides (MAP) of JC virus capsid protein (VP1) without cross reaction to BK virus: a diagnostic tool for progressive multifocal leukoencephalopathy.针对JC病毒衣壳蛋白（VP1）合成多抗原肽（MAP）且与BK病毒无交叉反应的抗体：一种进行性多灶性白质脑病的诊断工具。
Neurosci Lett. 1996 Feb 23;205(2):111-4. doi: 10.1016/0304-3940(96)12389-2.
3
Papovavirus detection by electron microscopy in the brain of an elderly patient without overt progressive multifocal leukoencephalopathy.在一名无明显进行性多灶性白质脑病的老年患者大脑中通过电子显微镜检测乳头多瘤空泡病毒。
Virchows Arch. 1994;424(5):569-72. doi: 10.1007/BF00191445.
4
Transmission of the human polyomavirus JC virus occurs both within the family and outside the family.人类多瘤病毒JC病毒的传播既发生在家庭内部，也发生在家庭外部。
J Clin Microbiol. 1994 Oct;32(10):2359-63. doi: 10.1128/jcm.32.10.2359-2363.1994.
5
Progressive multifocal leukoencephalopathy (PML): in vitro cell-mediated immune responses to mitogens and JC virus.进行性多灶性白质脑病（PML）：对丝裂原和JC病毒的体外细胞介导免疫反应
Neurology. 1980 Mar;30(3):256-62. doi: 10.1212/wnl.30.3.256.
6
Ultrastructural studies of fibroblasts transfected with hepatitis B virus DNA.对转染乙肝病毒DNA的成纤维细胞的超微结构研究。
Hepatology. 1984 Jan-Feb;4(1):84-9. doi: 10.1002/hep.1840040115.
7
Progressive multifocal leucoencephalopathy: detection of papovavirus JC in kidney tissue.进行性多灶性白质脑病：在肾脏组织中检测到乳头多瘤空泡病毒JC
J Med Virol. 1983;11(4):307-17. doi: 10.1002/jmv.1890110406.
8
Persistence of DNA sequences of BK virus and JC virus in normal human tissues and in diseased tissues.BK病毒和JC病毒的DNA序列在正常人体组织和患病组织中的持续性。
J Infect Dis. 1983 Apr;147(4):676-84. doi: 10.1093/infdis/147.4.676.
9
Distribution of nonintegrated DNA from JC papovavirus in organs of patients with progressive multifocal leukoencephalopathy.进行性多灶性白质脑病患者器官中JC多瘤病毒非整合DNA的分布
J Infect Dis. 1983 Apr;147(4):669-75. doi: 10.1093/infdis/147.4.669.
10
A prospective study of human polyomavirus infection in pregnancy.孕期人多瘤病毒感染的前瞻性研究。
J Infect Dis. 1980 Jul;142(1):1-8. doi: 10.1093/infdis/142.1.1.
Zotero 插件