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边缘番荔枝中的产乙酸菌及其它化合物及其抗原生动物活性。

Acetogenins and other compounds from Rollinia emarginata and their antiprotozoal activities.

作者信息

Février A, Ferreira M E, Fournet A, Yaluff G, Inchausti A, Rojas de Arias A, Hocquemiller R, Waechter A I

机构信息

Laboratoire de Pharmacognosie, BIOCIS URA 1843 CNRS, Faculté de Pharmacie, Châtenay-Malabry, France.

出版信息

Planta Med. 1999 Feb;65(1):47-9. doi: 10.1055/s-1999-13961.

DOI:10.1055/s-1999-13961
PMID:10083845
Abstract

Bioactivity-directed fractionation of the MeOH extract of the stem barks of Rollinia emarginata resulted in the isolation of six compounds, four acetogenins, rolliniastatin-1, sylvaticin, squamocin, and rollidecin B, one lignan, lirioresinol B, and an oxoaporphine, liriodenin. Their structures were determined by spectroscopic analysis and their in vitro leishmanicidal and trypanocidal properties are reported.

摘要

对边缘罗林果茎皮甲醇提取物进行生物活性导向分离,得到了六种化合物,四种产乙酸素,即罗林果他汀-1、森林菌素、鳞霉素和罗林德辛B,一种木脂素,即鹅掌楸树脂醇B,以及一种氧化阿朴啡,即鹅掌楸碱。通过光谱分析确定了它们的结构,并报道了它们的体外抗利什曼原虫和抗锥虫特性。

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