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冠状动脉搭桥手术后五年生活质量受损的决定因素。

Determinants of an impaired quality of life five years after coronary artery bypass surgery.

作者信息

Herlitz J, Wiklund I, Caidahl K, Karlson B W, Sjöland H, Hartford M, Haglid M, Karlsson T

机构信息

Division of Cardiology, Sahlgrenska University Hospital, S-413 45 Göteborg, Sweden.

出版信息

Heart. 1999 Apr;81(4):342-6. doi: 10.1136/hrt.81.4.342.

Abstract

OBJECTIVE

To identify determinants of an inferior quality of life (QoL) five years after coronary artery bypass grafting (CABG).

SETTING

University hospital.

PARTICIPANTS

Patients from western Sweden who underwent CABG between 1988 and 1991.

MAIN OUTCOME MEASURES

Questionnaires for evaluating QoL before CABG and five years after operation. Three different instruments were used: the Nottingham health profile (NHP), the psychological general wellbeing index (PGWI), and the physical activity score (PAS).

RESULTS

2121 patients underwent CABG, of whom 310 died during five years' follow up. Information on QoL after five years was available in 1431 survivors (79%). There were three independent predictors for an inferior QoL with all three instruments: female sex, a history of diabetes mellitus, and a history of chronic obstructive pulmonary disease. Multivariate analysis showed that a poor preoperative QoL was a strong independent predictor for an impaired QoL five years after CABG. An impaired QoL was also predicted by previous disease.

CONCLUSIONS

Female sex, an impaired QoL before surgery, and other diseases such as diabetes mellitus are independent predictors for an impaired QoL after CABG in survivors five years after operation.

摘要

目的

确定冠状动脉旁路移植术(CABG)五年后生活质量(QoL)较差的决定因素。

地点

大学医院。

参与者

1988年至1991年间在瑞典西部接受CABG的患者。

主要观察指标

CABG术前及术后五年评估QoL的问卷。使用了三种不同的工具:诺丁汉健康量表(NHP)、心理总体幸福感指数(PGWI)和身体活动评分(PAS)。

结果

2121例患者接受了CABG,其中310例在五年随访期间死亡。1431例幸存者(79%)有术后五年的QoL信息。使用所有三种工具得出,有三个独立的因素可预测QoL较差:女性、糖尿病史和慢性阻塞性肺疾病史。多变量分析显示,术前QoL较差是CABG术后五年QoL受损的一个强有力的独立预测因素。既往疾病也可预测QoL受损。

结论

女性、术前QoL受损以及糖尿病等其他疾病是术后五年CABG幸存者QoL受损的独立预测因素。

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