Mazza M, Montanari L, Pavanetto F
Farmaco Sci. 1976 Oct;31(10):746-54.
A series of N-acyl derivatives of indoline (A) was prepared and tested for phytotoxic activity. The substances studied (Tables I leads to III, substances I leads to XXVIII) were prepared by reaction of indoline with suitable acylating agents and were mainly new compounds. The biological tests consisted in pre- and post-emergence treatment in doses of 6 kg/ha or lower doses on five common weeds; one substance (XXV) was tested also on other species of economic importance (Table III). The results show that of the three classes studied the N-carbamoyl- and N-thiocarbamoyl derivatives of indoline have wide spectrum phytotoxic activity especialy on absorption via the foliage. The highest phytotoxic activity in both pre- and post-emergence tests was shown by N-(methylcarbamoyl)indoline (XIII) and N-(dimethylcarbamoyl(indoline (XXIII).
制备了一系列吲哚啉的N-酰基衍生物（A），并对其进行了植物毒性活性测试。所研究的物质（表I至III，物质I至XXVIII）通过吲哚啉与合适的酰化剂反应制备，主要为新化合物。生物测试包括对五种常见杂草进行6千克/公顷或更低剂量的苗前和苗后处理；一种物质（XXV）也在其他具有经济重要性的物种上进行了测试（表III）。结果表明，在所研究的三类物质中，吲哚啉的N-氨基甲酰基和N-硫代氨基甲酰基衍生物具有广泛的植物毒性活性，特别是通过叶片吸收。在苗前和苗后测试中，N-（甲基氨基甲酰基）吲哚啉（XIII）和N-（二甲基氨基甲酰基）吲哚啉（XXIII）表现出最高的植物毒性活性。
