Wetterlin S, Ericsson B F, Aronsen K F
Eur Surg Res. 1976;8(6):545-9. doi: 10.1159/000127901.
Standardized skin burn injuries were induced in 253 NMRI mice. The burned surface corresponded to 15% of the total surface of a 25-gram mouse. All animals received intraperitoneal injection of an isotonic saline solution in a dose of 20% of body weight/day for 5 days. The material was divided into three groups, i.e. group A (controls) which received no further treatment, groups B and C which, in addition, received triglycylvasopressin (a vasopressin with prolonged effect) 100 and 200 mug/kg body weight, respectively, subcutaneously twice a day. The highest survival rate was registered in group B (61%), while the controls had a survival of 36%.
对253只NMRI小鼠造成标准化的皮肤烧伤。烧伤面积相当于一只25克小鼠体表总面积的15%。所有动物每天腹腔注射等渗盐溶液，剂量为体重的20%，持续5天。材料被分为三组，即A组（对照组）不接受进一步治疗，B组和C组除上述处理外，分别每天皮下注射两次三甘氨酰加压素（一种长效加压素），剂量为100微克/千克体重和200微克/千克体重。B组的存活率最高（61%），而对照组的存活率为36%。
