Wetterlin S, Björkman I
Scand J Plast Reconstr Surg. 1977;11(2):109-13. doi: 10.3109/02844317709025506.
Cardiac output and regional blood flow to different organs were determined at one hour and at 24 hours after burn in untreated mice and in mice treated with triglycylvasopressin (TGLVP). A decrease in cardiac output was found in all animals at one hour after burn. At 24 hours cardiac output was decreased in the burned untreated group, while cardiac output of TGLVP-treated animals did not differ from that of unburned animals. Organ blood flow was decreased in all animals at one hour after burn. Such a decrease was seen in the untreated group also at 24 hours after burn, while organ blood flow in the TGLVP-treated group had returned to preburn values.
在未治疗的小鼠和用三甘氨酰加压素(TGLVP)治疗的小鼠中,于烧伤后1小时和24小时测定心输出量及不同器官的局部血流量。在烧伤后1小时,所有动物的心输出量均下降。在烧伤后24小时,未治疗的烧伤组心输出量下降,而经TGLVP治疗的动物的心输出量与未烧伤动物的无差异。在烧伤后1小时,所有动物的器官血流量均下降。在未治疗组中,烧伤后24小时也出现这种下降,而经TGLVP治疗组的器官血流量已恢复到烧伤前的值。