Nawawi A, Nakamura N, Hattori M, Kurokawa M, Shiraki K
Research Institute for Wakan-Yaku (Traditional Sino-Japanese Medicines), Toyama Medical and Pharmaceutical University, Japan.
Phytother Res. 1999 Feb;13(1):37-41. doi: 10.1002/(SICI)1099-1573(199902)13:1<37::AID-PTR382>3.0.CO;2-S.
Water and methanol extracts of 30 traditional medicinal plants, collected in Indonesia, were tested for their anti HSV-1 activity. The extracts of eight plant species showed potent activity on the plaque assay at a concentration of 100 micrograms/mL. The therapeutic efficacy of seven selected plants was demonstrated by using a mouse HSV-1 infection assay, both the methanol extracts of the fruit of Melaleuca leucadendron (Myrtaceae) and the pericarp of Nephelium lappaceum (Sapindaceae) significantly prolonged the development of skin lesions and reduced the mortality.
对采集自印度尼西亚的30种传统药用植物的水提取物和甲醇提取物进行了抗单纯疱疹病毒1型（HSV-1）活性测试。8种植物的提取物在浓度为100微克/毫升时，在蚀斑试验中显示出强效活性。通过小鼠HSV-1感染试验证明了7种选定植物的治疗效果，白千层（桃金娘科）果实的甲醇提取物和红毛丹（无患子科）果皮的甲醇提取物均显著延长了皮肤损伤的发展时间并降低了死亡率。
