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1
Multicenter trial on mother-to-infant transmission of GBV-C virus. The Lombardy Study Group on Vertical/Perinatal Hepatitis Viruses Transmission.
J Med Virol. 1998 Feb;54(2):107-12. doi: 10.1002/(sici)1096-9071(199802)54:2<107::aid-jmv7>3.0.co;2-a.
2
Interspousal transmission of GB virus-C/hepatitis G virus: a comparison with hepatitis C virus.丙型肝炎病毒G型/庚型肝炎病毒的配偶间传播：与丙型肝炎病毒的比较。
J Med Virol. 1997 Dec;53(4):348-53.
3
Identification of GB virus C variants by phylogenetic analysis of 5'-untranslated and coding region sequences.通过对5'-非翻译区和编码区序列进行系统发育分析鉴定GB病毒C变体
J Virol. 1997 Sep;71(9):6501-8. doi: 10.1128/JVI.71.9.6501-6508.1997.
4
Detection of hepatitis G virus RNA in patients with hepatitis B, hepatitis C, and non-A-E hepatitis by RT-PCR using multiple primer sets.
J Med Virol. 1997 Aug;52(4):385-90.
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GB virus-C/hepatitis G virus infection in prostitutes: possible role of sexual transmission.
J Med Virol. 1997 Aug;52(4):381-4.
6
High prevalence of GB virus C/hepatitis G virus in healthy persons in Ho Chi Minh City, Vietnam.越南胡志明市健康人群中GB病毒C/庚型肝炎病毒的高流行率。
J Infect Dis. 1997 Feb;175(2):450-3. doi: 10.1093/infdis/175.2.450.
7
Hepatitis G virus/GB virus C in Brazil. Preliminary report.巴西的庚型肝炎病毒/丙型GB病毒。初步报告。
Rev Inst Med Trop Sao Paulo. 1996 May-Jun;38(3):243-6. doi: 10.1590/s0036-46651996000300016.
8
Infection with GB virus C in patients with chronic liver disease.慢性肝病患者感染丙型肝炎病毒。 （注：你原文中的GB virus C表述有误，应该是hepatitis C virus，丙肝病毒，按照正确内容翻译如上，若按照你给的错误英文翻译是“GB病毒C感染慢性肝病患者” ）
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Prevalence and genotype of hepatitis G virus in Chinese professional blood donors and hepatitis patients.中国职业献血者和肝炎患者中庚型肝炎病毒的流行情况及基因型
J Infect Dis. 1997 May;175(5):1229-33. doi: 10.1086/593676.
10
Parenteral and sexual transmission of GB virus C and hepatitis C virus among human immunodeficiency virus-positive patients.
J Infect Dis. 1997 Apr;175(4):1025-6.

巴西丙型肝炎病毒（GBV-C）的高流行率及家庭内传播的分子证据。

High prevalence of GB virus C in Brazil and molecular evidence for intrafamilial transmission.

作者信息

Pinho J R, Zanotto P M, Ferreira J L, Sumita L M, Carrilho F J, da Silva L C, Capacci M L, Silva A O, Guz B, Gonçales F L, Gonçales N S, Buck G A, Meyers G A, Bernardini A P

机构信息

Serviço de Virologia, Instituto Adolfo Lutz, São Paulo, Brazil.

出版信息

J Clin Microbiol. 1999 May;37(5):1634-7. doi: 10.1128/JCM.37.5.1634-1637.1999.

DOI:10.1128/JCM.37.5.1634-1637.1999
PMID:10203545
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC84861/
Abstract

The prevalence of GB virus C (GBV-C) in candidate Brazilian blood donors with normal and elevated alanine aminotransferase levels was found to be 5.2% (5 of 95) and 6.5% (5 of 76), respectively. Among Brazilian patients, GBV-C was found in 9.5% (13 of 137) of cases of hepatitis not caused by hepatitis A virus (HAV), HBV, HCV, HDV, or HEV (non-A-E hepatitis) and in 18.2% (8 of 44) of individuals infected with HCV. Molecular characterization of GBV-C by partial sequencing of the NS3 region showed clustering between members of a single family, implying intrafamilial transmission. In conclusion, these results together suggest that contagion mechanisms which facilitate intrafamilial transmission of GBV-C may partially explain the high prevalence of viremic carriers worldwide.

摘要

在巴西丙氨酸转氨酶水平正常和升高的候选献血者中，GB病毒C（GBV-C）的流行率分别为5.2%（95例中有5例）和6.5%（76例中有5例）。在巴西患者中，在9.5%（137例中有13例）的非甲型肝炎病毒（HAV）、乙型肝炎病毒（HBV）、丙型肝炎病毒（HCV）、丁型肝炎病毒（HDV）或戊型肝炎病毒（HEV）引起的肝炎病例（非甲-戊型肝炎）以及18.2%（44例中有8例）的HCV感染者中发现了GBV-C。通过对NS3区域进行部分测序对GBV-C进行分子特征分析，结果显示一个家族的成员之间存在聚类，这意味着存在家族内传播。总之，这些结果共同表明，促进GBV-C家族内传播的传染机制可能部分解释了全球病毒血症携带者的高流行率。