Lu C L, Zou X, Orr W C, Chen J D
Lynn Institute for Healthcare Research, Oklahoma City, Oklahoma 73112, USA.
Dig Dis Sci. 1999 Apr;44(4):857-61. doi: 10.1023/a:1026698800742.
The aim of this study was to investigate the sympathovagal balance after meals by measuring the spectral analysis of heart rate variability (HRV). Nine healthy volunteers were enrolled in this study. The electrocardiogram (ECG) was recorded for 30 min in a fasting state and 60 min after a 500-kcal test meal. The HRV was derived from the ECG and was measured by power spectral analysis using fast-Fourier transform algorithm. It reveals two dominant spectral components. The low-frequency (LF) band reflects primarily sympathetic activity with some parasympathetic input. The high-frequency (HF) band is a reflection of parasympathetic (vagal) activity. The LF-to-HF ratio is considered a marker of sympathovagal balance. It was found that the postprandial LF-to-HF ratio, compared with the fasting state, was significantly increased at both the first 30 min (2.50 +/- 0.49 vs 1.78 +/- 0.33, P < 0.05) and the second 30 min (2.68 +/- 0.55 vs 1.78 +/- 0.33, P < 0.05). The postprandial HF diminished significantly at both the first (16.0 +/- 0.5 vs 21.8 +/- 4.2, P < 0.05) and the second (13.8 +/- 9.5 vs 21.8 +/- 4.2, P < 0.05) 30-min period. In conclusion, the postprandial sympathovagal ratio shows a sustained elevation lasting 1 hr, mainly attributed to diminished vagal activity.
本研究旨在通过测量心率变异性（HRV）的频谱分析来探究餐后交感神经与迷走神经的平衡。九名健康志愿者参与了本研究。在空腹状态下记录心电图（ECG）30分钟，并在摄入500千卡测试餐后记录60分钟。HRV由ECG得出，并使用快速傅里叶变换算法通过功率谱分析进行测量。它显示出两个主要的频谱成分。低频（LF）带主要反映交感神经活动，并伴有一些副交感神经输入。高频（HF）带反映副交感神经（迷走神经）活动。LF与HF的比值被认为是交感神经与迷走神经平衡的标志。结果发现，与空腹状态相比，餐后LF与HF的比值在最初30分钟（2.50±0.49对1.78±0.33，P<0.05）和第二个30分钟（2.68±0.55对1.78±0.33，P<0.05）均显著升高。餐后HF在最初30分钟（16.0±0.5对21.8±4.2，P<0.05）和第二个30分钟（13.8±9.5对21.8±4.2，P<0.05）均显著降低。总之，餐后交感神经与迷走神经的比值持续升高1小时，主要归因于迷走神经活动减弱。
