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来自毛泡桐的抗菌苯丙素糖苷

Antibacterial phenylpropanoid glycosides from Paulownia tomentosa Steud.

作者信息

Kang K H, Jang S K, Kim B K, Park M K

机构信息

College of Pharmacy, Seoul National University, Seoul, Korea.

出版信息

Arch Pharm Res. 1994 Dec;17(6):470-5. doi: 10.1007/BF02979128.

DOI:10.1007/BF02979128
PMID:10319161
Abstract

The butanol extract of Paulownia tomentosa stem showed antibacterial activity against Staphylococcus aureus (SG511, 285 and 503), Streptococcus pyogenes (A308 and A77) and Streptococcus faecium MD8b etc. The most active compound of the extract was identified to be campneoside I, which had a minimal inhibitory concentration (MIC) of 150 micrograms/ml against Streptococcus and Staphylococcus species. From such antibacterial activity, the methoxy group of campneoside I was postulated to be the essential element for the antibacterial activity.

摘要

毛泡桐茎的丁醇提取物对金黄色葡萄球菌(SG511、285和503)、化脓性链球菌(A308和A77)和粪肠球菌MD8b等具有抗菌活性。提取物中最具活性的化合物被鉴定为梓醇苷I,其对链球菌和葡萄球菌属的最低抑菌浓度(MIC)为150微克/毫升。基于这种抗菌活性,推测梓醇苷I的甲氧基是抗菌活性的关键元素。

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