Holmes E C
Wellcome Trust Centre for the Epidemiology of Infectious Disease, Department of Zoology, University of Oxford, UK.
Br Med Bull. 1998;54(3):533-43. doi: 10.1093/oxfordjournals.bmb.a011708.
Molecular epidemiology is an emerging science. The development of new and rapid protocols to isolate and identify pathogens, coupled with the sophisticated phylogenetic analysis of their gene sequences, is providing a new and fascinating insight into the biology, origin and spread of infectious diseases. In this essay, I describe some of the ways in which the techniques of modern molecular biology and evolution have equipped us to face the challenge of these new infections.
分子流行病学是一门新兴科学。用于分离和鉴定病原体的新的快速方法的发展，再加上对其基因序列进行复杂的系统发育分析，正在为我们提供关于传染病的生物学、起源和传播的全新且引人入胜的见解。在本文中，我将描述现代分子生物学和进化技术使我们能够应对这些新感染挑战的一些方式。
