Podder Goutam, Breiman Robert F, Azim Tasnim, Thu Hlaing Myat, Velathanthiri Niluka, Mai Le Quynh, Lowry Kym, Aaskov John G
Center for Health and Population Research, International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka, Bangladesh.
Am J Trop Med Hyg. 2006 Feb;74(2):263-5.
Dengue and dengue hemorrhagic fever re-emerged in Bangladesh in 2000 and 2001 and nearly all viruses isolated were dengue type 3. Phylogenetic analyses of the envelope genes of examples of these viruses indicated that they were most closely related to recently emerged dengue type 3 viruses from neighboring Thailand and Myanmar but distinct from those from India and Sri Lanka. Since this strain of dengue virus type 3 had not been associated with unusual patterns of disease in Thailand or Myanmar, it suggested that the outbreak in Bangladesh was due to local factors after the introduction of viruses from countries to the east rather than to the evolution of an unusually virulent strain of virus in Bangladesh.
登革热和登革出血热于2000年和2001年在孟加拉国再度出现,几乎所有分离出的病毒都是3型登革热病毒。对这些病毒样本的包膜基因进行系统发育分析表明,它们与最近从邻国泰国和缅甸出现的3型登革热病毒关系最为密切,但与来自印度和斯里兰卡的病毒不同。由于这种3型登革热病毒株在泰国或缅甸并未与异常的疾病模式相关联,这表明孟加拉国的疫情爆发是由于从东部国家引入病毒后的当地因素,而非孟加拉国出现了异常毒力的病毒株的进化。