属于巴西流行克隆III::B:A的多重耐药金黄色葡萄球菌临床分离株中莫匹罗星耐药性的出现。

Emergence of mupirocin resistance in multiresistant Staphylococcus aureus clinical isolates belonging to Brazilian epidemic clone III::B:A.

作者信息

Ramos R L B, Teixeira L A, Ormonde L R, Siqueira P L A, Santos M S, Marangoni D, Figueiredo A M S

机构信息

Universidade Federal do Rio de Janeiro, Instituto de Microbiologia Prof. Paulo de Góes, Laboratório de Biologia Molecular de Bactérias, Centro de Ciěncias da Saúde, Bloco I, Cidade Universitária, Rio de Janeiro, RJ 21941.590, Brazil.

The Rockefeller University, 1230 York Avenue 10021, New York, NY, USA.

出版信息

J Med Microbiol. 1999 Mar;48(3):303-307. doi: 10.1099/00222615-48-3-303.

DOI:10.1099/00222615-48-3-303

PMID:10334598

Abstract

Mupirocin is a topical antimicrobial agent that has been successfully used to eradicate methicillin-resistant Staphylococcus aureus from the anterior nares and other sites of patients and health care personnel. This report describes the acquisition of a novel mupirocin resistance gene (ileS) by an epidemic MRSA clone that is geographically widespread in Brazil.

摘要

莫匹罗星是一种局部用抗菌剂，已成功用于清除患者和医护人员前鼻孔及其他部位的耐甲氧西林金黄色葡萄球菌。本报告描述了一种在巴西广泛传播的流行耐甲氧西林金黄色葡萄球菌克隆获得一种新的莫匹罗星耐药基因（ileS）的情况。