Pal S, Sen T, Chaudhuri A K
Department of Pharmaceutical Technology, Jadavpur University, Calcutta, India.
J Pharm Pharmacol. 1999 Mar;51(3):313-8. doi: 10.1211/0022357991772312.
Neuropharmacological studies were conducted in experimental animals (rats and mice) with the methanolic fraction of Bryophyllum pinnatum leaf extract. The fraction produced alteration of behaviour pattern, caused dose-dependent potentiation of pentobarbitone sleeping time and had significant analgesic activity. Significant reduction of exploratory behaviour and loss of residual curiosity were among the effects observed with the fraction. The observations suggest that the methanolic fraction of Bryophyllum pinnatum possesses a potent CNS depressant action.
使用落地生根叶提取物的甲醇提取物在实验动物（大鼠和小鼠）身上进行了神经药理学研究。该提取物导致行为模式改变，引起戊巴比妥睡眠时间的剂量依赖性增强，并具有显著的镇痛活性。该提取物还观察到探索行为显著减少和残留好奇心丧失等效应。这些观察结果表明，落地生根的甲醇提取物具有强大的中枢神经系统抑制作用。
