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[决定因素在个体发育过程中系统联系形成中的作用]

[Role of the determinance factor in formation of systemic connections during ontogenesis].

作者信息

Kokina N N

出版信息

Fiziol Zh SSSR Im I M Sechenova. 1976 Nov;62(11):1582-91.

PMID:1035546
Abstract

Behaviour of differentiating neuroblasts was studied in the nervous tissue culture of the newborn rats cortex and medulla oblongata of the rabbit embryo. The phasic-contrast microscopy and study of fixated preparations revealed that distribution of the neuroblasts over the substrate, their mutual orientation, the character of their branches growth and formation of contacts occur in vitro involving certain stages of morphological forming of the brain systemic organization. The clear trend of the neuroblasts behaviour to formation of certain connections suggests their genetic determinance. The distribution of neuroblasts over the substrate from different brain areas has its own phenotypic features.

摘要

在新生大鼠皮质以及兔胚胎延髓的神经组织培养中,对分化中的神经母细胞的行为进行了研究。相差显微镜检查以及对固定标本的研究显示,神经母细胞在底物上的分布、它们的相互取向、其分支生长的特征以及接触的形成,都是在体外发生的,且涉及脑系统组织形态形成的某些阶段。神经母细胞行为呈现出形成特定连接的明显趋势,这表明它们具有遗传决定性。来自不同脑区的神经母细胞在底物上的分布具有其自身的表型特征。

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