Navarro-Alarcón M, López-Garcia de la Serrana H, Pérez-Valero V, López-Martínez C
Department of Nutrition and Bromatology, Faculty of Pharmacy, University of Granada, Granada, Spain.
Ann Nutr Metab. 1999;43(1):30-6. doi: 10.1159/000012764.
Serum and urine selenium levels were determined in patients with cardiovascular diseases by hydride generation atomic absorption spectrometry. Mean serum Se concentrations measured in patients with acute myocardial infarction (AMI; n = 32) or with ischemic cardiomyopathy (n = 50) were significantly lower than those determined in control groups. In AMI patients, serum triglyceride levels showed a positive significant correlation with the serum Se concentration (r = 0.59, p < 0.05). This result reinforces the important role of Se as an antioxidant agent in this disease. Mean urine Se concentrations of AMI patients (n = 33) were also significantly lower to those determined in the control group (p < 0. 05). This reaction of the organism contributes to regulate the Se homeostasis to keep the body Se status as high as possible.
采用氢化物发生原子吸收光谱法测定心血管疾病患者的血清和尿液硒水平。在急性心肌梗死患者（n = 32）或缺血性心肌病患者（n = 50）中测得的平均血清硒浓度显著低于对照组。在急性心肌梗死患者中，血清甘油三酯水平与血清硒浓度呈显著正相关（r = 0.59，p < 0.05）。这一结果强化了硒作为抗氧化剂在该疾病中的重要作用。急性心肌梗死患者（n = 33）的平均尿硒浓度也显著低于对照组（p < 0.05）。机体的这种反应有助于调节硒的稳态，以使身体的硒状态尽可能保持在较高水平。
