Cerri D, Ebani V V, Pedrini A, Nuvoloni R, Renzoni G, Andreani E, Farina R
Department of Animal Pathology, Prophylaxis and Food Hygiene, Faculty of Veterinary Medicine, University of Pisa, Italy.
New Microbiol. 1999 Jul;22(3):227-31.
Ten sexually immature rams were experimentally infected with Brucella ovis, to verify the antibody kinetics and its localization in urinary and genital tracts. All animals became positive to the complement fixation test from the 2nd post infection (p.i.) week and reached the maximum titre (1:256) on the 4th p.i. week. Bacteriemia was demonstrated on 3rd, 4th and 5th p.i. weeks. Two animals, respectively slaughtered 11 and 13 weeks after the infection, showed macroscopic and microscopic genital lesions and the etiologic agent was cultured from their urine and genital organs.
选用10只性未成熟的公羊，通过实验感染绵羊布鲁氏菌，以验证抗体动力学及其在泌尿生殖道中的定位。所有动物在感染后（p.i.）第2周补体结合试验呈阳性，并在感染后第4周达到最高滴度（1:256）。在感染后第3、4和5周检测到菌血症。分别在感染后11周和13周屠宰的两只动物，表现出肉眼可见和显微镜下可见的生殖器病变，并且从它们的尿液和生殖器官中培养出了病原体。
