生物钟
Biological clocks.
作者信息
Ishida N, Kaneko M, Allada R
机构信息
Ishida Group of Clock Gene, National Institute of Bioscience and Human Technology, Agency of Industrial Science and Technology, Ministry of International Trade and Industry, 1-1 Higashi, Tsukuba Science City, Ibaraki 305 Japan.
出版信息
Proc Natl Acad Sci U S A. 1999 Aug 3;96(16):8819-20. doi: 10.1073/pnas.96.16.8819.
Abstract
Circadian rhythms describe biological phenomena that oscillate with an approximately 24-hour cycle. These rhythms include blood pressure, body temperature, hormone levels, the number of immune cells in blood, and the sleep-wake cycle. In this paper, we will focus on common genes between species that are responsible for determining the circadian behavior, especially some transcription factors (i.e., switch genes) that serve to regulate many circadian rhythm genes. The intent of this summary is to introduce the common molecular mechanism of biological clocks between flies and humans and then to describe the research from three laboratories that was presented in the session.
摘要
昼夜节律描述了以大约24小时周期振荡的生物现象。这些节律包括血压、体温、激素水平、血液中免疫细胞的数量以及睡眠-清醒周期。在本文中，我们将重点关注物种间负责决定昼夜行为的共同基因，尤其是一些用于调节许多昼夜节律基因的转录因子（即开关基因）。本综述的目的是介绍果蝇和人类生物钟的共同分子机制，然后描述在该会议上展示的来自三个实验室的研究。
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本文引用的文献
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