Kessel L, Alsing A, Larsen M
Department of Ophthalmology, Herlev Hospital, University of Copenhagen, Denmark.
Br J Ophthalmol. 1999 Sep;83(9):1042-5. doi: 10.1136/bjo.83.9.1042.
To examine whether the colour vision abnormalities found in phakic patients with diabetes mellitus is preserved after removal of the lens by cataract surgery.
21 diabetic (16 IDDM and five NIDDM) and 19 non-diabetic patients of comparable age, postoperative visual acuity, and sex distribution, all aphakic or pseudophakic following cataract surgery, had their monocular colour vision examined using the Farnsworth-Munsell 100 hue test. The fundus status of the diabetic patients ranged from no retinopathy to photocoagulation treated proliferative diabetic retinopathy. Patients with macular oedema were specifically excluded from the study.
The error scores of both the diabetic (mean 146 (SD 94)) and the non-diabetic patients (83 (79)) did not deviate significantly from the age related normal range. The error score in the diabetic group was significantly higher than in the non-diabetic group (p=0.02) but the amplitude of the difference was small in comparison with previous studies of phakic subjects. The error scores in the diabetic group were not correlated with the degree of retinopathy (p>0.2).
After cataract surgery only a minor difference exists between the colour vision scores of diabetic and non-diabetic patients. This indicates that accelerated yellowing of the lens in diabetes is the predominant cause of the colour vision anomaly found in phakic diabetic patients.
研究患有糖尿病的有晶状体患者在白内障手术摘除晶状体后,其存在的色觉异常是否依然存在。
21例糖尿病患者(16例胰岛素依赖型糖尿病和5例非胰岛素依赖型糖尿病)以及19例年龄、术后视力和性别分布与之相当的非糖尿病患者,均在白内障手术后为无晶状体或人工晶状体眼,使用 Farnsworth-Munsell 100色调试验对其单眼色觉进行检查。糖尿病患者的眼底状况从无视网膜病变到接受光凝治疗的增殖性糖尿病视网膜病变不等。黄斑水肿患者被特意排除在本研究之外。
糖尿病患者(平均146(标准差94))和非糖尿病患者(83(79))的误差评分均未显著偏离与年龄相关的正常范围。糖尿病组的误差评分显著高于非糖尿病组(p = 0.02),但与之前对有晶状体受试者的研究相比,差异幅度较小。糖尿病组的误差评分与视网膜病变程度无关(p>0.2)。
白内障手术后,糖尿病患者和非糖尿病患者的色觉评分仅存在微小差异。这表明糖尿病患者晶状体加速变黄是有晶状体糖尿病患者色觉异常的主要原因。