利斯特菌细胞壁组分对人B淋巴细胞的刺激作用。
Stimulation of human B lymphocytes by Listeria cell wall fraction.
作者信息
Ivanyi L
出版信息
Clin Exp Immunol. 1978 Nov;34(2):193-8.
Abstract
Cell wall fraction of Listeria monocytogenes (LCWF), a B cell mitogen for mouse spleen cells, is also mitogenic for human adult and cord peripheral blood lymphocytes. Purified B-cell suspensions responded to LCWF in vitro proliferation, to a similar extent as the unfractionated suspensions. Furthermore, LCWF-induced B cell differentiation into IgM-containing cells and their percentage correlated significantly with the extent of lymphocyte proliferation.
摘要
单核细胞增生李斯特菌细胞壁组分（LCWF）是小鼠脾细胞的B细胞有丝分裂原，对成人和脐带外周血淋巴细胞也有促有丝分裂作用。纯化的B细胞悬液对LCWF的体外增殖反应程度与未分级悬液相似。此外，LCWF诱导B细胞分化为含IgM的细胞，其百分比与淋巴细胞增殖程度显著相关。
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