先天性感染胎儿母亲羊水中人巨细胞病毒DNA的定量分析。
Quantification of human cytomegalovirus DNA in amniotic fluid of mothers of congenitally infected fetuses.
作者信息
Revello M G, Zavattoni M, Furione M, Baldanti F, Gerna G
机构信息
Servizio di Virologia, IRCCS Policlinico San Matteo, 27100 Pavia, Italy.
出版信息
J Clin Microbiol. 1999 Oct;37(10):3350-2. doi: 10.1128/JCM.37.10.3350-3352.1999.
Abstract
A quantitative PCR assay was used to quantitate human cytomegalovirus DNA in amniotic fluid of mothers of 21 fetuses with congenital infection. Seven fetuses presented ultrasound abnormalities or were born with symptoms, whereas 14 fetuses were subclinically infected. Although the median DNA level was higher in symptomatic fetuses, the difference was not statistically significant (P = 0.09).
摘要
采用定量聚合酶链反应检测法对21例先天性感染胎儿母亲羊水中的人巨细胞病毒DNA进行定量分析。7例胎儿出现超声异常或出生时有症状，而14例胎儿为亚临床感染。虽然有症状胎儿的DNA水平中位数较高，但差异无统计学意义（P = 0.09）。
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