Canosi U, Ferrari E, Falaschi A, Mazza G
J Bacteriol. 1979 Jan;137(1):124-8. doi: 10.1128/jb.137.1.124-128.1979.
We have studied the effect of 6-(p-hydroxyphenylazo)-uracil on the recombination processes that operate in the homologous and heterologous transduction mediated by PBS1 and SP10 phages of Bacillus subtilis. The results obtained demonstrate that the process of heterologous genetic exchange is sensitive to this compound, whereas the homologous process is not. The present data, along with those of our previous work (U. Canosi, A. G. Siccardi, A. Falaschi, and G. Mazza, J. Bacteriol. 126:108--121, 1976), suggest that the DNA polymerase III is involved in the recombination process that operates in transformation and heterologous transduction, whereas homologous transduction follows a partially independent pathway not involving this protein.
我们研究了6-（对羟基苯偶氮）尿嘧啶对枯草芽孢杆菌PBS1和SP10噬菌体介导的同源和异源转导中发生的重组过程的影响。所得结果表明，异源基因交换过程对该化合物敏感，而同源过程则不敏感。目前的数据，连同我们先前工作的结果（U. 卡诺西、A. G. 西卡尔迪、A. 法拉斯基和G. 马扎，《细菌学杂志》126:108 - 121，1976年）表明，DNA聚合酶III参与转化和异源转导中发生的重组过程，而同源转导则遵循一条部分独立的途径，不涉及该蛋白质。
