Barykina N N, Aksenovich T I, Alekhina T A, Chuguĭ V G, Kolpakov V G
Institute of Cytology and Genetics, Russian Academy of Sciences, Novosibirsk, Russia.
Genetika. 1999 Jul;35(7):956-60.
Inheritance of predisposition to pendulum movements (PMs) in rats was studied by two methods: segregation analysis of binary traits (on pedigrees recorded in the selection archives for cataleptic strain GC) and the classical Mendelian analysis of hybrids between strains PM+ and PM- selected for pronounced PMs and the absence of PMs, respectively. Both methods yields the same result: it was found that predisposition to PMs exhibited a monogenic dominant inheritance with incomplete penetrance.
对二元性状进行分离分析(基于强直性昏厥品系GC选择档案中记录的系谱),以及对分别因明显摆动运动和无摆动运动而选择的PM +和PM -品系之间的杂种进行经典孟德尔分析。两种方法得出了相同的结果:发现摆动运动易感性表现为单基因显性遗传,且外显率不完全。