Svendsen U G, Munck O, Czartoryski A, Stafanger G
Scand J Clin Lab Invest. 1978 Dec;38(8):777-9. doi: 10.1080/00365517809104887.
Comparison of [51Cr]EDTA plasma clearance corrected for extrarenal elimination with 24 h endogenous creatinine clearance in patients with advanced renal failure showed that the corrected [51Cr]EDTA clearance was lower than creatinine clearance, and thus might be a better approximation to the glomerular filtration rate in uraemic patients. The corrections cannot be used on [51cr]EDTA clearance values below the mean extrarenal clearance, averaging 3.7 ml/min.
对晚期肾衰竭患者经肾外清除校正的[51Cr]依地酸血浆清除率与24小时内生肌酐清除率进行比较,结果显示校正后的[51Cr]依地酸清除率低于肌酐清除率,因此对于尿毒症患者的肾小球滤过率而言,校正后的[51Cr]依地酸清除率可能是更好的近似值。对于低于平均肾外清除率(平均为3.7毫升/分钟)的[51Cr]依地酸清除率值,不能进行校正。