Berges R R, Pientka L
Department of Urology, Marienhospital Herne, Ruhr-Universität Bochum, Herne, Germany.
Eur Urol. 1999;36 Suppl 3:21-7. doi: 10.1159/000052345.
To review the available data on contemporary management of symptomatic benign prostatic hyperplasia (BPH) within the German healthcare system.
Information was obtained from articles published in scientific journals retrieved through searches in Medline and Embase. In addition, preliminary data from the first representative German survey on lower urinary tract symptoms (LUTS) were obtained ('Herner LUTS-Study', a community-based survey in Herne, a city within the industrial complex called the Ruhr Area). Finally, the recently established German guidelines for the diagnosis and treatment of the BPH-Syndrom (BPS) were reviewed.
Only few studies are published in the literature analysing the current concepts of management of BPH in Germany. These studies show that there is variation in the concepts of conservatory and surgical management of BPH. The German BPH guidelines suggest watchful waiting for patients with mild LUTS (total I-PSS < or = 7) and medical therapy or surgery for those with moderate to severe LUTS (I-PSS >7). There was no final consensus on the role of phytotherapy in the German treatment guidelines, due to the lack of clinical data. alpha(1)-Blockers and finasteride (for prostates >40 ml) are recommended medical treatment approaches. Transurethral resection of the prostate (TUR-P) is considered to be the standard surgical procedure. Preliminary data from the Herner LUTS-Study show, that approximately 30% of men aged 50-80 years have moderate to severe LUTS (i.e. total I-PSS score >7). About a third of these men currently seek healthcare.
LUTS and BPS are a highly prevalent condition in Germany. With the estimate that the number of men over the age of 65 will almost double in Germany within the next 30 years, it will be a challenge in the next millennium to find the healthcare resources for the management of BPS. Copyrightz1999S. KargerAG,Basel
回顾德国医疗体系中有关有症状良性前列腺增生(BPH)当代管理的现有数据。
信息来源于通过检索Medline和Embase获取的科学期刊发表文章。此外,还获取了德国首次关于下尿路症状(LUTS)的代表性调查的初步数据(“赫纳LUTS研究”,一项在鲁尔区工业综合体中的城市赫纳进行的基于社区的调查)。最后,对最近制定的德国BPH综合征(BPS)诊断和治疗指南进行了回顾。
文献中仅有少数研究分析了德国BPH管理的当前概念。这些研究表明,BPH的保守治疗和手术治疗概念存在差异。德国BPH指南建议,轻度LUTS患者(总国际前列腺症状评分[I-PSS]≤7)采用观察等待,中度至重度LUTS患者(I-PSS>7)采用药物治疗或手术治疗。由于缺乏临床数据,植物疗法在德国治疗指南中的作用尚未达成最终共识。α1受体阻滞剂和非那雄胺(用于前列腺体积>40 ml者)是推荐的药物治疗方法。经尿道前列腺切除术(TUR-P)被认为是标准的外科手术。赫纳LUTS研究的初步数据显示,50-80岁男性中约30%有中度至重度LUTS(即总I-PSS评分>7)。这些男性中约三分之一目前寻求医疗服务。
LUTS和BPS在德国是一种高度普遍的疾病。预计在未来30年内,德国65岁以上男性数量将几乎翻倍,在下一个千年中,为BPS管理寻找医疗资源将是一项挑战。版权所有©1999 S. Karger AG,巴塞尔