El-Refaie M, Tait R, Dulake C, Dische F E
Postgrad Med J. 1976 Aug;52(610):497-500. doi: 10.1136/pgmj.52.610.497.
Pneumococcal capsular antigens can be detected in lung tissue by counter-current immunoelectrophoresis even when, following antibiotics, post-mortem bacterilogy suggests that Escherichia coli has replaced pneumococci. The results suggest that antipneumococcal therapy would benefit at least 55% of patients critically ill with lung infection and that the potentially toxic drugs directed at coliform bacteria may be unnecessary.
即使在使用抗生素后尸检细菌学显示大肠杆菌已取代肺炎球菌的情况下，仍可通过对流免疫电泳在肺组织中检测到肺炎球菌荚膜抗原。结果表明，抗肺炎球菌治疗将使至少55%的重症肺部感染患者受益，而针对大肠菌的潜在有毒药物可能是不必要的。
