格雷夫斯病患者的眼动脉搏动幅度：一项初步研究。
Ocular pulse amplitude in patients with Graves' disease: a preliminary study.
作者信息
Alimgil M L, Benian O, Esgin H, Erda S
机构信息
Trakya University Medical School, Department of Ophthalmology, Edirne, Turkey.
出版信息
Acta Ophthalmol Scand. 1999 Dec;77(6):694-6. doi: 10.1034/j.1600-0420.1999.770618.x.
PURPOSE
The purpose of this study was to evaluate the ocular pulse amplitude changes in patients with Graves' disease.
METHODS
The pulse amplitudes of 31 patients with Graves' disease were measured with the OBF-Tonograph (OBF Labs UK). All patients were in the euthyroid phase of the disease. 17 patients (Group I) had no ocular involvement or only mild lid retraction. 14 patients (Group II) had either proptosis and/or extraocular muscle involvement. Only the worst involved eye of each patient was included into the study.
RESULTS
There was no statistically significant difference between the two groups among the parameters which might influence the pulse amplitude measurement. The pulse amplitude was statistically significantly lower in Group II than in Group I (2.34+/-0.79 and 3.22+/-0.94 mmHg respectively, p<0.013).
CONCLUSION
Pulse amplitude measurements may be an important discrimination and classification parameter for patients with ophthalmic Graves' disease.
目的
本研究旨在评估格雷夫斯病患者的眼动脉搏动幅度变化。
方法
使用OBF眼压描记仪（英国OBF实验室）测量31例格雷夫斯病患者的搏动幅度。所有患者均处于疾病的甲状腺功能正常阶段。17例患者（第一组）无眼部受累或仅有轻度眼睑退缩。14例患者（第二组）有眼球突出和/或眼外肌受累。仅将每位患者受累最严重的一只眼睛纳入研究。
结果
在可能影响搏动幅度测量的参数方面，两组之间无统计学显著差异。第二组的搏动幅度在统计学上显著低于第一组（分别为2.34±0.79和3.22±0.94 mmHg，p<0.013）。
结论
搏动幅度测量可能是格雷夫斯眼病患者重要的鉴别和分类参数。
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