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非活动期格雷夫斯眼病黄斑及黄斑旁微血管密度与视网膜血管管径改变的分析

Analysis of Foveal and Parafoveal Microvascular Density and Retinal Vessel Caliber Alteration in Inactive Graves' Ophthalmopathy.

作者信息

Akpolat Cetin, Kurt Muhammed M, Yılmaz Merve, Ordulu Fikriye, Evliyaoglu Ferhat

机构信息

Department of Ophthalmology, Sisli Hamidiye Etfal Training and Research Hospital, İstanbul, Turkey.

Department of Ophthalmology, Samsun Gazi Community Hospital, Samsun, Turkey.

出版信息

J Ophthalmol. 2020 Mar 19;2020:7643737. doi: 10.1155/2020/7643737. eCollection 2020.

Abstract

PURPOSE

We aimed to evaluate foveal and parafoveal density using optical coherence tomography angiography and the alteration on the retinal vessel diameter in patients with inactive Graves' ophthalmopathy compared to age-matched normal population. . Patients with inactive Graves' ophthalmopathy (study group) and healthy individuals (control group) were enrolled in the cross sectionally designed study. The optical coherence tomography angiography parameters and retinal vessel diameter measurements were assessed between the study and control groups. Foveal and parafoveal microvascular density in the retina was measured using optical coherence tomography angiography. Retinal artery and vein diameter and artery/vein ratio were assessed for retinal vessel caliber changes.

RESULTS

Patients with inactive Graves' ophthalmopathy had higher values of intraocular pressure, proptosis, and axial length (=0.001, =0.001, =0.001, =0.001, =0.001, =0.001, =0.001, =0.001, =0.001, =0.001, =0.001.

CONCLUSION

Optical coherence tomography angiography could be a novel and promising noninvasive diagnostic technique in patients with inactive Graves' ophthalmopathy to detect foveal and parafoveal vessel density changes compared to healthy subjects. The decrease of retinal vessel diameter might be observed in patients with inactive graves ophthalmopathy.

摘要

目的

我们旨在使用光学相干断层扫描血管造影术评估静止期格雷夫斯眼病患者的黄斑中心凹和黄斑旁密度,并与年龄匹配的正常人群相比,观察其视网膜血管直径的变化。将静止期格雷夫斯眼病患者(研究组)和健康个体(对照组)纳入横断面设计的研究。评估研究组和对照组之间的光学相干断层扫描血管造影参数和视网膜血管直径测量值。使用光学相干断层扫描血管造影术测量视网膜黄斑中心凹和黄斑旁微血管密度。评估视网膜动脉和静脉直径以及动脉/静脉比率以观察视网膜血管管径变化。

结果

静止期格雷夫斯眼病患者的眼压、眼球突出度和眼轴长度值更高(=0.001,=0.001,=0.001,=0.001,=0.001,=0.001,=0.001,=0.001,=0.001,=0.001,=0.001)。

结论

与健康受试者相比,光学相干断层扫描血管造影术可能是一种用于静止期格雷夫斯眼病患者检测黄斑中心凹和黄斑旁血管密度变化的新型且有前景的非侵入性诊断技术。静止期格雷夫斯眼病患者可能会观察到视网膜血管直径减小。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/84f0/7125468/9fba95210539/JOPH2020-7643737.001.jpg

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