Tchuendem M H, Mbah J A, Tsopmo A, Ayafor J F, Sterner O, Okunjic C C, Iwu M M, Schuster B M
Chemistry Department, Faculty of Science, University of Dschang, Cameroon.
Phytochemistry. 1999 Nov;52(6):1095-9. doi: 10.1016/s0031-9422(99)00344-1.
A new isodaucane sesquiterpenoid, 6,7,10-trihydoxyisodaucane, was isolated from the fruits of Reneilmia cincinnata, together with the known sesquiterpenoids oplodiol, oplopanone, 5E,10(14)-germacradien-1 beta, 4 beta-diol, 1(10)E,5E-germacradien-4 alpha-ol and eudesman-1,4,7-triol. A large amount of 5-hydroxy-3,7,4'-trimethoxyflavone was also isolated. Their structures were established by NMR techniques using 1D and 2D experiments. Three of the known sesquirernenoids exhibited noteworthy anti-plasmodial activity against Plasmodium falciparum strains.
