Dewit O, Fuller N J, Fewtrell M S, Elia M, Wells J C
Clinical Pharmacology Department, SmithKline Beecham Pharmaceuticals, New Frontiers Science Park (South), Third Avenue, Harlow CM19 5AW, UK.
Arch Dis Child. 2000 Feb;82(2):159-64. doi: 10.1136/adc.82.2.159.
To assess the acceptability and feasibility of whole body air displacement plethysmography in children and to determine its precision and agreement with hydrodensitometry, an appropriate reference method.
Age specific two component model equations were used to predict fat mass from body density in 22 children aged 8-12 years and in 10 adults for comparison of methods. Precision for each method was established from duplicate measurements.
Plethysmography was accepted more readily than hydrodensitometry (100% v 69% provided duplicate measurements). Precision for fat mass in children was 0.38 kg by plethysmography and 0.68 kg by hydrodensitometry, and results were similar in adults. The mean (SD) fat mass in children was 6.9 kg (4.0) and 6.7 kg (4. 2) by plethysmography and hydrodensitometry, respectively, but 95% limits of agreement between methods were large (-4.1 kg to 3.5 kg fat).
Plethysmography was more readily accepted and had better precision than hydrodensitometry. It also provided similar body composition results for the group but not for all individual children.
评估儿童全身空气置换体积描记法的可接受性和可行性,并确定其与合适的参考方法——水下密度测量法相比的精度和一致性。
使用年龄特异性双组分模型方程,根据22名8至12岁儿童和10名成年人的身体密度预测脂肪量,以比较不同方法。每种方法的精度通过重复测量来确定。
体积描记法比水下密度测量法更容易被接受(提供重复测量的比例分别为100%和69%)。儿童脂肪量的体积描记法精度为0.38千克,水下密度测量法为0.68千克,成年人的结果相似。儿童通过体积描记法和水下密度测量法测得的平均(标准差)脂肪量分别为6.9千克(4.0)和6.7千克(4.2),但两种方法之间的95%一致性界限范围较大(脂肪量为-4.1千克至3.5千克)。
体积描记法比水下密度测量法更容易被接受且精度更高。它为该组人群提供了相似的身体成分结果,但并非适用于所有个体儿童。