Clare L, Wilson B A, Carter G, Breen K, Gosses A, Hodges J R
Sub-department of Clinical Health Psychology, University College London, United Kingdom.
J Clin Exp Neuropsychol. 2000 Feb;22(1):132-46. doi: 10.1076/1380-3395(200002)22:1;1-8;FT132.
Dementia of Alzheimer Type (DAT) is increasingly detected at an earlier stage of the disorder, when interventions to assist with everyday memory difficulties might be most valuable. Some learning is possible in DAT and a number of factors have been identified which may facilitate performance, although applications to everyday memory problems have been limited. The concept of errorless learning has not previously been directly examined in relation to DAT, but might provide a useful additional strategy. In the present study, 6 participants with early stage DAT (MMSE scores 21 - 26) received individually tailored interventions, based on errorless learning principles and targeted at a specific everyday memory problem. Five of the participants showed significant improvement on the target measures, and maintained this improvement up to 6 months later. The results suggest that it is feasible to intervene with everyday memory problems in the early stages
阿尔茨海默病型痴呆（DAT）越来越多地在该疾病的早期阶段被检测出来，此时针对日常记忆困难的干预措施可能最有价值。在DAT中仍存在一定的学习能力，并且已经确定了一些可能促进表现的因素，尽管这些因素在解决日常记忆问题方面的应用有限。此前尚未直接研究无错误学习概念与DAT的关系，但它可能提供一种有用的额外策略。在本研究中，6名早期DAT患者（简易精神状态检查表评分21 - 26）接受了基于无错误学习原则并针对特定日常记忆问题的个性化干预。其中5名参与者在目标测量上有显著改善，并在6个月后仍保持这种改善。结果表明，在早期阶段干预日常记忆问题是可行的。
