Rohrschneider K, Bültmann S, Glück R, Kruse F E, Fendrich T, Völcker H E
Department of Ophthalmology, University of Heidelberg, Germany.
Am J Ophthalmol. 2000 Jan;129(1):27-32. doi: 10.1016/s0002-9394(99)00270-6.
To prospectively evaluate functional and funduscopic changes after laser treatment in patients with diabetic retinopathy and clinically significant macular edema by scanning laser ophthalmoscope fundus perimetry.
Thirty eyes of 30 patients with clinically significant macular edema as a result of diabetic retinopathy were prospectively examined before and at least 3 months after focal laser treatment with automatic fundus threshold perimetry using the scanning laser ophthalmoscope. Thresholds of light sensitivity were compared with age-corrected normal values and correlated with corrected visual acuity and subjective appraisal of visual function.
In 30 eyes, fundus perimetry lasted for 10.5+/-2.7 (mean+/-SD) minutes with 322+/-67 stimulus presentations for each eye. Whereas eight eyes remained stable (< +/-1 dB change), 15 improved concerning mean deviation (MD) (3.1+/-1.7 dB) after focal laser treatment. Stability of fixation remained the same after focal laser treatment (0.75+/-0.57 degree). Laser scars showed marked loss of function (MD > 13 dB).
Although light sensitivity was reduced in areas of macular edema, there was no correlation between the amount of edema and visual function. Fundus perimetry allows the creation of exact maps of retinal dysfunction before and after laser treatment. It may help in making management decisions in diabetic and nondiabetic patients by offering a sensitive parameter in addition to visual acuity.
通过扫描激光检眼镜眼底视野计,前瞻性评估糖尿病视网膜病变合并具有临床意义的黄斑水肿患者激光治疗后的功能和眼底变化。
对30例因糖尿病视网膜病变导致具有临床意义的黄斑水肿患者的30只眼,在进行局灶性激光治疗前及治疗后至少3个月,使用扫描激光检眼镜通过自动眼底阈值视野计进行前瞻性检查。将光敏感度阈值与年龄校正后的正常值进行比较,并与矫正视力和视觉功能的主观评估相关联。
30只眼中,眼底视野计检查每只眼持续10.5±2.7(平均值±标准差)分钟,有322±67次刺激呈现。8只眼保持稳定(变化<±1 dB),15只眼在局灶性激光治疗后平均偏差(MD)有所改善(3.1±1.7 dB)。局灶性激光治疗后注视稳定性保持不变(0.75±0.57度)。激光瘢痕显示功能明显丧失(MD>13 dB)。
尽管黄斑水肿区域的光敏感度降低,但水肿程度与视觉功能之间无相关性。眼底视野计能够绘制激光治疗前后视网膜功能障碍的精确图谱。除视力外,它还能提供一个敏感参数,有助于对糖尿病和非糖尿病患者做出治疗决策。